Skip to content
Search AI Powered

Latest Stories

New Study: Is Natural Psilocybin As Good As Synthetic Psilocybin?

If synthetic psilocybin proves to be just as good as the real thing, what would it mean for the emerging industry?
If synthetic psilocybin proves to be just as good as the real thing, what would it mean for the emerging industry?

This article was originally published on Benzinga and appears here with permission.

Numinus Wellness announced the launch of a new clinical trial that will add information to an industry insider debate: is naturally produced psilocybin as good as synthetic psilocybin?


Numinus’ new Phase I clinical trial, to be conducted in partnership with , will test out the company’s own naturally derived psilocybin formulation on human subjects.

The trial will enroll 14 healthy volunteers and will assess the safety and psychoactive properties of a Psilocybe mushroom formulation extracted at the Numinus Bioscience lab in British Columbia.

The company holds a license to cultivate and extract magic mushrooms in Canada.

As opposed to most psilocybin clinical trials today, Numinus’ study uses a derivative of natural mushrooms instead of a synthesized version of the plant.

The company did not clarify whether the formulation contains isolated psilocybin derived from natural mushrooms, or a full-spectrum formulation, which would include psilocybin and other natural tryptamines.

“We believe there are several likely advantages to naturally occurring Psilocybin therapeutics that will make them attractive for researchers and consumers alike,” said Sharan Sidhu, science officer and general manager at Numinus Bioscience.

 “We are confident that this trial will document that natural Psilocybin extractions meet health regulator requirements for safety, efficacy and quality, and ultimately enable the establishment of better access to this medicine,” she added.

Need a little more Bluntness in your life? Check out our YouTube page

More For You

image of dried psychedelic mushrooms

Magic mushrooms come in more strains than you might realize - The Bluntness

Ultimate Guide: Magic Mushroom Strains

What Makes Psilocybin Mushroom Strains Different? {#strains-vs-species}

Magic mushrooms aren't one-size-fits-all. Like cannabis strains, different varieties of psilocybin mushrooms deliver vastly different experiences based on their chemical composition.

Strains vs. Species: What's the Actual Difference?

Here's the deal: species are broad categories of closely related mushrooms sharing similar DNA and characteristics. Strains are sub-groups within a species, like cousins in the same family.

Keep ReadingShow less
Sex on shrooms is not for everyone, although certainly worth a try -- perhaps with a bit of guidance first.
Sex on shrooms is not for everyone, although certainly worth a try -- perhaps with a bit of guidance first.

Sex on Shrooms: How to Prepare Yourself

If you've tripped on psilocybin (a.k.a., magic mushrooms) before, you're already well aware what an intense experience it can be. And if shrooms can take an average activity like listening to music to an entirely different universe, you can probably imagine what sex on shrooms might feel like.

As intense and amazing as mushroom sex can be, it can also be an incredibly negative experience if you're not careful. Most psychotropic substances are best experienced when you curate the right set and setting, and sex on magic mushrooms is no different.

Keep ReadingShow less
Store your psilocybin mushrooms properly for best results.
Store your psilocybin mushrooms properly for best results.
Photo by Marco Allegretti on Unsplash

Psilocybin 101: How to Store Magic Mushrooms to Maximize Potency and Shelf Life

Magic mushrooms, or psilocybin mushrooms, have been embraced for their transformative effects and potential therapeutic benefits. However, like any organic material, they are perishable and can lose potency—or worse, become unsafe—if not stored correctly. Whether you're healing depression or having trippy sex to hallucinatory entertainment, understanding how to properly store your mushrooms can help you preserve their effects for months or even years.

This comprehensive guide outlines best practices, advanced techniques, and essential tips for safely storing magic mushrooms to maintain their potency and avoid spoilage.

Keep ReadingShow less
Getting you ready for your first magic mushroom trip - The Bluntness

Getting you ready for your first magic mushroom trip - The Bluntness

How Long Do Shrooms Last? Magic Mushroom Guide for Beginners

In 2022, general interest in magic mushrooms has spiked to unprecedented levels not seen since the 1960s. Thanks to research showing promising results for patients, lawmakers a handful of states and cities already have or are considering loosening psilocybin restrictions.

A few states such as Oregon have fully legalized psilocybin treatment for all adult patients, while others want to limit it to veterans or others with PTSD.

Keep ReadingShow less
Magic mushrooms taste gross. Let's fix that.
Magic mushrooms taste gross. Let's fix that.

6 Ways to Consume Magic Mushrooms (that don't involve a peanut butter sandwich)

If you have ever consumed magic mushrooms or truffles, then you know they don’t always have the most pleasant taste, in fact, some of them are like eating a mouthful of dirt.  

However, with the recent rise of popularity through legalization, decriminalization, and the public becoming more aware of the benefits and potential good that comes with these psilocybin-packed fungi, we see why people may overlook the flavor.

Keep ReadingShow less